Unveiling the molecular basis of T cell malfunctions and disorders using quantitative interactomics
Bernhard Malissen, Marseille (FR)26th Meeting on Signal Transduction
November 6 - 8, 2023 - Leonardo Hotel Weimar
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Jointly organized by:
As in previous years, the 26th STS Meeting will be organized as a Joint Meeting of the Signal Transduction Society with signaling study groups of the German Societies for Immunology (DGfI) and Cell Biology (DGZ), the Society for Biochemistry and Molecular Biology (GBM), the German Society for Pharmacology (DGP), and the Collaborative Research Center "Structural Dynamics of GPCR Activation and Signaling" (SFB1423). This year, we are delighted to welcome the Centre for Integrative Biological Signalling Studies (CIBSS) as new co-organizer of the meetin. If other organizations are interested in joining future STS Meetings, please contact the STS President Prof. Dr. Klaudia Giehl.
Workshops 2023
Planned Workshops:
Immune Cell Signaling
Special Workshop: 25 years of STS
Hot Topics in Signal Transduction
STS / CIBSS joint workshop:
From Basic Research to InnovationG-Protein Signaling
Differentiation, Stress, and Death
Tumor Cell Biology
Infection and Inflammation
As in previous years, sponsoring companies will have the opportunity to present their innovative products for signal transduction research as a 15 min plenary lecture in a Workshop session. These presentations will conclude the Workshop sessions to allow for further discussions with the companies’ representatives at their booths during the following breaks.
Program
Each Workshop/Session will start with introductory keynote presentations of 30 minutes (including discussion) given by invited speakers who have contributed significantly to the development of specific areas of signal transduction research. Keynote speakers are nominated by STS members and contributing consortia.
All presentations will be given as plenary lectures in the main conference hall. There will be no parallel workshop sessions. Oral presentations will be selected from the submitted abstracts (abstract submission deadline: September 24, 2023).
A limited number of abstracts will be selected for oral presentation of 10 minutes plus 5 minutes of discussion. The oral presentations are thematically related to the Workshop topics. They will be selected by the organizing committee on the basis of scientific quality and consistency with the scientific program.
Nov 4
10:30
Registration & Welcome Coffee
12:30
Welcome Note
12:45
Workshop Immune Cell Signaling
Local tissue microenvironment, immunometabolism, and host defense
Jonathan Jantsch, Köln (DE)Immune-complex induced neutrophil kinase signalling in pemphigoid disease
Mareile SchlotfeldtThe MK2/MK3/TTP hub determines the composition and balance of cytokine expression in MCMV-infected macrophages
Christian EhltingLigand-independent constitutive cytokine receptor signaling mediated by forced transmembrane dimerization
Doreen Floss14:45
Coffee break
15:15
STS General Assembly
16:30
My Poster in a Nutshell talks
17:00
Poster viewing I
18:30
Dinner
19:30
Workshop Hot Topics in Signal Transduction
A question of dynamics
Barbara di Ventura, Freiburg (DE)Regulatory T cells in tissues: from fundamental research to engineered applications
Markus Feuerer, Regensburg (DE)Computational pipelines based on Artificial Intelligence – a versatile low-threshold tool for biomedicine
Julian BorbeckOptogenetic Control of the Mitochondrial Protein Import in Mammalian Cells
Lukas Althoff21:00
Get-together in Hotel Gallery
Nov 5
08:30
Workshop Growth Factors, Cytokines, and Their Receptors
Synthetic interleukin 6 cytokine signaling
Jürgen Scheller, Düsseldorf (DE)Mechanisms of TNFR activation - From understanding to generic design principles for TNFR agonists
Harald Wajant, Würzburg (DE)A TNFR2-specific TNF fusion protein with improved vaccine effectiveness
Yin XiaoThe novel function of GANP, a member of Transcription Export Complex 2 (TREX-2) in the transcription regulation of immediate early genes
Doan Duy Hai TranProtein Succinylome analysis identifies citrate synthase as a central regulator of osteoclast differentiation
Yue Gao10:30
Coffee break
11:00
Workshop From Basics to Translation
Inflammasome signaling as a gateway to addressing inflammatory diseases
Mohamed Lamkanfi, Genth (BE)Combining precision oncology and immunotherapy by targeting the MALT1 protease
Daniel Krappmann, München (DE)A multi-lineage 3D culture system to model tumor cells in non-transformed microenvironment
Alexandra KochAberrant expression of the MID1 protein in Huntington's disease brain
Sybille KraußNovel application of Promega NanoBiT® Protein:Protein Interaction System
Annika Reisbitzer13:00
Lunch Snack
13:45
Workshop G Protein-Mediated Signaling
GPCRs in the Era of Biobanks
Alexander Hauser, Copenhagen (DK)Contribution of orphan GPCR signaling to the control of energy homeostasis
Julien Hanson, Liége (BE)Exploring the Ligand-Induced Stabilization of the Active Y4 Receptor Conformation by Using Selective Peptide Agonists
Tim PelczykRas localization in the context of SPRED1 regulated Retromer trafficking
Sarah BühlerMammalian hydroxycarboxylic acid receptor 2 is under changing evolutionary constraint
Claudia Stäubert15:45
Coffee break
16:00
Poster Viewing II
18:00
STS Honorary Medal Award Ceremony
Deconvoluting the complexity of protein phosphorylation and the protein kinases involved
Lewis C. Cantley, Boston / MA 02115 (US)19:30
Dinner
Nov 6
08:45
Workshop Tumor Cell Biology
Mechanobiology in cancer progression: the role of cell mechanics in glioblastoma invasion and therapeutic resistance
Sandrine Etienne-Manneville, Paris (FR)Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a xenotransplantation model
Manfred JückerTargeting Dual-Specificity Phosphatases DUSP1 and DUSP6 in Drug-Resistant Chronic Lymphocytic Leukemia
Maike BuchnerThe Emerging Tumor Suppressor RFX7 is a Potential Regulator for Differentiation Therapy in Acute Myeloid Leukemia
Setenay Gupse Özcan10:15
Coffee break
10:45
Workshop Differentiation, Stress, and Death
Autophagy in immune metabolism, differentiation and aging
Katja Simon, Berlin (DE)IRGQ-Mediated Autophagy in MHC-I Quality Control Drives Tumor Immune Evasion
Lina HerhausER stress inhibition enhances formation of triacylglcerols and protects endothelial cells from lipotoxicity
Igor KovacevicRole of MRTF in breast epithelial differentiation and function
Anna Burova12:00
Announcement of Raffle Winners
12:15
Workshop Infection and Inflammation
Macrophage production of the immune-metabolite itaconate: the swiss-army knife in immunoregulation and anti-bacterial defence?
Roland Lang, Erlangen (DE)Use of the cytoskeleton to control Shigella infection
Serge Mostowy, London (GB)Regulation of the cGAS/STING pathway by Staphylococcus aureus biofilm environments
Elisabeth SeebachMono-ADP-ribosylation in antiviral defense
Patricia KornBRG1 and glucocorticoids – more than gene activation
Franziska Greulich14:00
Presentation of Awards
14:15
Farewell Snack / End of Meeting
Registration and Fees
The STS aims at making the meeting attractive and affordable especially for young scientists.
As in recent years, the regular meeting fees cover lunches, dinners (without beverages) and catering during coffee breaks and poster sessions throughout the meeting. Moreover, the traditional personalized STS coffee mug are also included in the registration fees.
Register here for the meeting!Please note that accomodation costs are not included in the meeting fee, so you are free to arrange bookings by yourself.
We would like to stress that the fees for STS members do not even cover the effective costs for individual participants.
Congress Venue
The STS Meeting will again take place in the Leonardo Hotel Weimar, located in the world heritage city of Weimar, Germany.
Accomodation rates at the congress hotel are usually quite low as compared to other hotels located in the city centre. You can reach the congress venue starting from the central train station by bus (line 1 / direction Ehringsdorf --> get out at "Falkenburg" bus stop) or by taking a stroll (takes you about 40 minutes).
If you travel by car, you may either choose to park at the hotel's own parking lot or parking garage (charges apply) or search free parking space in the adjacent streets.
Abstract Submission
The deadline for abstract submission was September 24. Changes can still be made - please contact the webmaster.
By 13 October 2023 at the latest, you will be informed by e-mail about further details, e.g. date, time and type of presentation (if you have chosen "Talk or Poster").
Poster Sessions
All accepted poster contributions will be on display (poster format: DIN A0, upright, 84,1 cm x 118,9 cm) throughout the Meeting in an assigned poster area together with the sponsors’ exhibition. This comfortable area can be used for vivid discussions at the posters during the coffee breaks. Ample time will be reserved for poster viewing and discussion.
“My Poster in a nutshell" presentations
In addition, all accepted posters can be presented to the plenum in one of the Short Talk Sessions as a concise One-Minute-Short talk. Please prepare one PowerPoint Slide containing key aspects of your scientific contribution to attract participants to your poster. After the short talk presentation it will be possible to meet at the posters for further scientific disussions.
STS Honorary Medal 2023
The STS honorary medal represents the most prestigious award of the STS. The medal is presented every year to an outstanding scientist who inspired scientists all over the world to work on receptors, mediators or genes involved in signal transduction processes. The Medal Ceremonies with informative Laudations and the Medal Award Lectures are meanwhile established highlights of the conference.
A list of Past Recipients of the STS Honorary Medal is available.
Prizes and Travel Grants
STS Science Award
This prize is meant to honor outstanding research by a post doc or a junior principal investigator being member of the Signal Transduction Society. In 2023, the STS Science Award will be donated with a sum of 1500,- Euro.
The jury board consisting of the STS council and STS advisory board members will evaluate the applicants’ scientific achievements and background in general and discuss the meeting contributions in detail in order to finally take their decision on the awardee.
GBM-Innovation-Award for Young Scientists
Each year on the occasion of the STS Joint Meeting “Signal Transduction - Receptors, Mediators and Genes”, the Society for Biochemistry and Molecular Biology/Gesellschaft für Biochemie und Molekularbiologie e.V. (GBM) announces the GBM-Innovation-Award for Young Scientists, donated with EUR 500,–.
The prize will be granted to a young scientist (diploma, master, MD or PhD student or post doc within their first years) who is developing or has developed a novel and innovative method, which might be attractive for all of us. The work has to be submitted as an abstract to the STS-Meeting and must be presented also as a poster, even if the abstract is selected for oral presentation. The awardee will be announced at the Award ceremony. Awards can only be received personally.
The award jury consisting of the speakers of the GBM-Study Groups “Biochemical Pharmacology and Toxicology” and “Receptors and Signal Transduction” will select appropriate candidates.
STS travel stipends
In 2023, the STS decided to award ten young scientists travel stipends (300 EUR each).
For more details, please also refer to the Prizes / Travel grants section of our website.
Poster Prizes
Five poster prizes will be awarded during the meeting. The candidates will be selected by the chair people of the different sessions.
The prize money will be paid by bank transer, provided that the prize winners attend the award ceremony in person.
Company Raffle
The participating companies have again generously sponsored prizes. All you have to do to win one of them is go to the company booths and talk to the representatives. For this you get a sticker with the logo of the company, which you put on the entry form enclosed in the booklet. The more stickers collected, the higher the chance of winning one of the coveted prizes. The sheet can then be dropped into the lottery box set up at the registration desk or handed in to the staff there by 9 a.m. on Wednesday, 6 November 2024 the latest.
The prizes will be awarded on Wednesday between the last two workshops of the meeting.
Sponsors of the STS Meeting 2023
The industrial exhibition of sponsoring companies will take place in an approximately 400 square meter area together with the poster exhibition in order to concentrate and facilitate interactions between the conference participants and the industry.
We are very grateful to all companies who want to support the STS Meeting.
If you are interested in sponsoring the meeting, please contact Katharina Hieke-Kubatzky.
Sponsors of the meeting as of 9.10.2023 are:
Committees
The STS is a non-profit organization that currently represents around 350 scientists. Over the past years, we have developed a fairly efficient and cost-saving routine for the Meeting organization. The Meeting is organized as a Joint Meeting of the STS with signaling study groups of the German Societies for Immunology (DGfI) and Cell Biology (DGZ), the Society for Biochemistry and Molecular Biology (GBM), the German Society for Pharmacology (DGP), and the Collaborative Research Center "Structural Dynamics of GPCR Activation and Signaling" (SFB1423). This year, we are delighted to welcome the Centre for Integrative Biological Signalling Studies (CIBSS) as new co-organizer of the meeting.
STS Council
Klaudia Giehl, Gießen
Katharina Hieke-Kubatzky, Heidelberg
Ingo Schmitz, Bochum
Detlef Neumann, Hannover
STS Advisory Board
Friederike Berberich-Siebelt, Würzburg
Dirk Brenner, Luxemburg
Arnd Kieser, München
Alexandra Koch, Hannover
Marcus Lettau, Kiel
Jonathan Lindquist, Magdeburg
Norbert Reiling, Borstel
Bastian Schirmer, Hannover
STS Council and STS Advisory Board
Chairpeople of contributing study groups and consortia
Chairpeople of individual workshops
Bastian Schirmer, Hannover
Annette Stanke, Hannover
Philipp Busse, Hannover
Bastian Schirmer, Hannover