27th Meeting on Signal Transduction
November 4 - 6, 2024 - Leonardo Hotel Weimar
Jointly organized by:
As in previous years, the 27th STS Meeting will be organized as a Joint Meeting of the Signal Transduction Society with signaling study groups of the German Societies for Immunology (DGfI) and Cell Biology (DGZ), the Society for Biochemistry and Molecular Biology (GBM), the German Society for Pharmacology (DGP), and the Collaborative Research Center "Structural Dynamics of GPCR Activation and Signaling" (SFB1423). If other organizations are interested in joining future STS Meetings, please contact the STS President Prof. Dr. Katharina Hieke-Kubatzky.
This year, travel expenses of our international invited speakers were also funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – project number 551082666.
Workshops
Planned Workshops:
A) Immune Cell Signaling
B) Hot Topics in Signal Transduction
C) Growth Factors, Cytokines, and Their Receptors
D) From Basics to Translation
E) G-Protein Mediated Signaling
F) Tumor Cell Biology
G) Differentiation, Stress, and Death
H) Infection and Inflammation
As in previous years, sponsoring companies will have the opportunity to present their innovative products for signal transduction research as a 15 min plenary lecture in a Workshop session. These presentations will conclude the Workshop sessions to allow for further discussions with the companies’ representatives at their booths during the following breaks.
Program
Each Workshop/Session will start with introductory keynote presentations of 30 minutes (including discussion) given by invited speakers who have contributed significantly to the development of specific areas of signal transduction research. Keynote speakers are nominated by STS members and contributing consortia.
All presentations will be given as plenary lectures in the main conference hall. There will be no parallel workshop sessions. Oral presentations will be selected from the submitted abstracts (new abstract submission deadline: September 15, 2024).
A limited number of abstracts will be selected for oral presentation of 10 minutes plus 5 minutes of discussion. The oral presentations are thematically related to the Workshop topics. They will be selected by the organizing committee on the basis of scientific quality and consistency with the scientific program.
Registration & Welcome Coffee
Welcome Note
Workshop Immune Cell Signaling
Unveiling the molecular basis of T cell malfunctions and disorders using quantitative interactomics (GBM lecture)
Local tissue microenvironment, immunometabolism, and host defense
Immune-complex induced neutrophil kinase signalling in pemphigoid disease
The MK2/MK3/TTP hub determines the composition and balance of cytokine expression in MCMV-infected macrophages
Ligand-independent constitutive cytokine receptor signaling mediated by forced transmembrane dimerization
Updates on the Andor Dragonfly and BC43: Versatile Confocal Microscopes for Advanced Imaging
Coffee break
STS General Assembly
My Poster in a Nutshell talks
Poster viewing I
Dinner
Workshop Hot Topics in Signal Transduction
A question of dynamics
Regulatory T cells in tissues: from fundamental research to engineered applications
Computational pipelines based on Artificial Intelligence – a versatile low-threshold tool for biomedicine
Optogenetic Control of the Mitochondrial Protein Import in Mammalian Cells
Get-together in Hotel Gallery
Workshop Growth Factors, Cytokines, and Their Receptors
Synthetic interleukin 6 cytokine signaling
Mechanisms of TNFR activation - From understanding to generic design principles for TNFR agonists
A TNFR2-specific TNF fusion protein with improved vaccine effectiveness
The novel function of GANP, a member of Transcription Export Complex 2 (TREX-2) in the transcription regulation of immediate early genes
Protein Succinylome analysis identifies citrate synthase as a central regulator of osteoclast differentiation
BMG LABTECH’s microplate readers for cell signalling assays
Coffee break
Workshop From Basics to Translation
Inflammasome signaling as a gateway to addressing inflammatory diseases
Combining precision oncology and immunotherapy by targeting the MALT1 protease
A multi-lineage 3D culture system to model tumor cells in non-transformed microenvironment
Aberrant expression of the MID1 protein in Huntington's disease brain
Novel application of Promega NanoBiT® Protein:Protein Interaction System
Seeing is Believing: Functional Imaging of NanoLuc® Technologies with Bioluminescence Microscopy
Lunch Snack
Workshop G Protein-Mediated Signaling
GPCRs in the Era of Biobanks
Contribution of orphan GPCR signaling to the control of energy homeostasis
Exploring the Ligand-Induced Stabilization of the Active Y4 Receptor Conformation by Using Selective Peptide Agonists
Ras localization in the context of SPRED1 regulated Retromer trafficking
Mammalian hydroxycarboxylic acid receptor 2 is under changing evolutionary constraint
Studying signal transduction pathways by gene expression
Coffee break
Poster Viewing II
STS Honorary Medal Award Ceremony
Deconvoluting the complexity of protein phosphorylation and the protein kinases involved (GBM lecture)
Dinner
Workshop Tumor Cell Biology
Mechanobiology in cancer progression: the role of cell mechanics in glioblastoma invasion and therapeutic resistance
Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a xenotransplantation model
Targeting Dual-Specificity Phosphatases DUSP1 and DUSP6 in Drug-Resistant Chronic Lymphocytic Leukemia
The Emerging Tumor Suppressor RFX7 is a Potential Regulator for Differentiation Therapy in Acute Myeloid Leukemia
AI-Powered High Content Imaging and Analysis with Nikon's Eclipse Ji
Coffee break
Workshop Differentiation, Stress, and Death
Autophagy in immune metabolism, differentiation and aging
IRGQ-Mediated Autophagy in MHC-I Quality Control Drives Tumor Immune Evasion
ER stress inhibition enhances formation of triacylglcerols and protects endothelial cells from lipotoxicity
Role of MRTF in breast epithelial differentiation and function
Announcement of Raffle Winners
Workshop Infection and Inflammation
Macrophage production of the immune-metabolite itaconate: the swiss-army knife in immunoregulation and anti-bacterial defence?
Use of the cytoskeleton to control Shigella infection
Regulation of the cGAS/STING pathway by Staphylococcus aureus biofilm environments
Mono-ADP-ribosylation in antiviral defense
BRG1 and glucocorticoids – more than gene activation
Presentation of Awards
Farewell Snack / End of Meeting
Congress Venue
The STS Meeting will again take place in the Leonardo Hotel Weimar, located in the world heritage city of Weimar, Germany.
Leonardo Hotel Weimar
Belvederer Alle 25 - 99425 Weimar
Accomodation rates at the congress hotel are usually quite low as compared to other hotels located in the city centre. You can reach the congress venue starting from the central train station by bus (line 1 / direction Ehringsdorf --> get out at "Falkenburg" bus stop) or by taking a stroll (takes you about 40 minutes).
If you travel by car, you may either choose to park at the hotel's own parking lot or parking garage (charges apply) or search free parking space in the adjacent streets.
Poster Sessions
All accepted poster contributions will be on display (poster format: DIN A0, upright, 84,1 cm x 118,9 cm) throughout the Meeting in an assigned poster area together with the sponsors’ exhibition. This comfortable area can be used for vivid discussions at the posters during the coffee breaks. Ample time will be reserved for poster viewing and discussion.
“My Poster in a nutshell" presentations
In addition, all accepted posters can be presented to the plenum in one of the Short Talk Sessions as a concise One-Minute-Short talk. Please prepare one PowerPoint Slide containing key aspects of your scientific contribution to attract participants to your poster. After the short talk presentation it will be possible to meet at the posters for further scientific disussions.
Prizes and Travel Grants
STS Science Award
This prize is meant to honor outstanding research by a post doc or a junior principal investigator being member of the Signal Transduction Society. In 2024, the STS Science Award will be donated with a sum of 1500,- Euro.
The jury board consisting of the STS council and STS advisory board members will evaluate the applicants’ scientific achievements and background in general and discuss the meeting contributions in detail in order to finally take their decision on the awardee.
GBM-Innovation-Award for Young Scientists
Each year on the occasion of the STS Joint Meeting “Signal Transduction - Receptors, Mediators and Genes”, the Society for Biochemistry and Molecular Biology/Gesellschaft für Biochemie und Molekularbiologie e.V. (GBM) announces the GBM-Innovation-Award for Young Scientists, donated with EUR 500,–.
The prize will be granted to a young scientist (diploma, master, MD or PhD student or post doc within their first years) who is developing or has developed a novel and innovative method, which might be attractive for all of us. The work has to be submitted as an abstract to the STS-Meeting and must be presented also as a poster, even if the abstract is selected for oral presentation. The awardee will be announced at the Award ceremony. Awards can only be received personally.
The award jury consisting of the speakers of the GBM-Study Groups “Biochemical Pharmacology and Toxicology” and “Receptors and Signal Transduction” will select appropriate candidates.
STS travel stipends
In 2024, the STS will award ten young scientists travel stipends (300 EUR each).
For more details, please also refer to the Prizes / Travel grants section of our website.
Poster Prizes
Five poster prizes will be awarded during the meeting. The candidates will be selected by the chair people of the different sessions.
The prize money will be paid by bank transfer, provided that the prize winners attend the award ceremony in person.
Sponsors of the STS Meeting
The industrial exhibition of sponsoring companies will take place in an approximately 400 square meter area together with the poster exhibition in order to concentrate and facilitate interactions between the conference participants and the industry.
We are very grateful to all companies who want to support the STS Meeting.
If you are interested in sponsoring the meeting, please contact Katharina Hieke-Kubatzky. The subscription for industrial sponsors can be downloaded here:
Sponsors of the meeting as of 09.07.2024 are:
Sponsors of the Meeting 2024
STS Council
Katharina Hieke-Kubatzky, Heidelberg
Jonathan Lindquist, Magdeburg
Klaudia Giehl, Gießen
Detlef Neumann, Hannover
STS Advisory Board
Friederike Berberich-Siebelt, Würzburg
Dirk Brenner, Luxemburg
Arnd Kieser, München
Alexandra Koch, Hannover
Norbert Reiling, Borstel
Bastian Schirmer, Hannover
Ingo Schmitz, Bochum
Sjoerd van Wijk, Frankfurt a.M.
Sabine Wolter, Hannover
STS Council and STS Advisory Board
Chairpeople of contributing study groups and consortia
Chairpeople of individual workshops
Bastian Schirmer, Hannover
Tina Hagedorn, Hannover
Philipp Busse, Hannover
Bastian Schirmer, Hannover